A Critical Reflection on Automated Science by Marta Bertolaso & Fabio Sterpetti

Author:Marta Bertolaso & Fabio Sterpetti
Language: eng
Format: epub
ISBN: 9783030250010
Publisher: Springer International Publishing

Moreover, diagrams such as the ones presented in Fig. 1 are rarely considered complete. They are “mechanism sketches” in the language of Machamer et al. (2000). Experiments often do not conclusively establish whether the activity of a molecular entity is sufficient to achieve an observed effect, which is reflected in biologists’ cautious formulations, such as the following:

Although the destruction of cyclin is necessary to inactivate MPF, it is currently unclear whether it alone is sufficient for the inactivation of MPF. One additional protein that may be required for the inactivation of MPF is p13, the product of the fission yeast suc1 gene […]. (Murray and Kirschner 1989).

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